Real Madrid vs Osasuna | Prediction | Lineups | ODDS | Date: August 19, 2025 | Venue: Santiago Bernabéu | La Liga Opener
The La Liga 2025/26 season kicks off with a tantalizing fixture as Real Madrid vs Osasuna at the iconic Santiago Bernabéu. Fans will be eager to see if Madrid can assert their dominance early, or if Osasuna can spring a surprise on the white giants.
Prediction:Real Madrid 2–1 Osasuna Key Players: Kylian Mbappé & Vinicius Jr & Jude Bellingham. (Real Madrid) | Defensive Focus: Osasuna
Madrid head into this opener with high expectations. With Mbappé and Vinicius Jr. spearheading the attack, they are primed to challenge Osasuna’s backline at every opportunity. Real Madrid’s new signings and emerging talents, such as Franco Mastantuono, could also make an impact, giving them fresh options in midfield and attack. However, the team isn’t without challenges. Jude Bellingham is sidelined until late October, and Eduardo Camavinga’s fitness is still in question, potentially leaving a gap in the midfield that Osasuna could exploit.
On the other side, Osasuna will approach this game with a solid defensive mindset*. Coach Alessio Lisci has been preparing his squad meticulously, focusing on strategies to contain Madrid’s firepower. Osasuna’s counter-attacks could prove dangerous if Madrid’s midfield loses control of the tempo. While they are clear underdogs, a disciplined and organized defensive performance could make the game much closer than expected.
Oddshttps://oddspedia.com/football/real-madrid-osasuna-82: Madrid Win ~65% | Draw ~18% | Osasuna Win ~12%
Over/Under 2.5 Goals: 58% chance of over
Tactically, Madrid are expected to dominate possession, using quick transitions and intelligent movement to break through Osasuna’s defensive lines. Osasuna, meanwhile, will likely stick to a 4-3-3 formation, staying compact at the back and seeking opportunities to hit Madrid on the counter. Fans can expect a battle of patience and precision, with Madrid trying to unlock a well-drilled defensive side.

Match Insight:
Expect a thrilling opening clash. Real Madrid are favorites, but Osasuna’s discipline could make them work hard for every goal. If Madrid’s attacking stars fire on all cylinders, a narrow victory seems likely. Watch for Mbappé’s runs and Vinicius Jr.’s flair, while Osasuna tries to frustrate the home side and capitalize on any mistakes. This matchup promises excitement, goals, and a taste of what this La Liga season might bring something new.